BackgroundGlaucoma is a leading cause of irreversible blindness globally and for decades, Molteno and Ahmed glaucoma implants, operating on different mechanisms, have been used to treat complicated glaucoma with varying success.ObjectiveTo assess the safety and efficacy of the Molteno glaucoma implant (MGI) versus the Ahmed glaucoma valve (AGV) in
Background Immunotherapy emerged as a promising treatment option for multiple myeloma (MM) patients.However, therapeutic efficacy can be hampered by the presence of an immunosuppressive bone marrow microenvironment including myeloid cells.S100A9 was previously identified as a key regulator of myeloid cell accumulation and suppressive activity.Tasqu
The existing sealing methods for goaf along gob-side entry retaining mainly focus on building sealing walls and sealing wall cracks.The construction period is long and repeated, which consumes a lot of labor costs, has a low degree of automation, and is prone to secondary damage.In order to solve the above problems, an automatic sealing system for
Background Tumor immune microenvironment (TIME) and cancer antigen expression, key factors for the development of immunotherapies, are usually based on the data from primary tumors due to availability of tissue for analysis; data from metastatic sites and their concordance with primary tumor are lacking.Although of the same origin from primary tumo